diff --git a/CMakeLists.txt b/CMakeLists.txt
index 1f2bd9c3fdc5406b9661de0b0f675b3153176fad..94399912eef06b7757bde9f55f2c35b4dd8cece7 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -185,6 +185,9 @@ export(EXPORT ${project}-targets
 ##############################################
 ## Add test
 if(TEST)
+    if(PYBIND)
+        message(FATAL_ERROR "PYBIND and TEST are enable. But cannot compile with catch_2.\nChoose between pybind and Catch2 for compilation.")
+    endif()
     enable_testing()
     add_subdirectory(unit_tests)
 endif()